AN ANALYSIS OF ABNORMALITIES IN THE B CELL RECEPTOR REPERTOIRE IN PATIENTS WITH SYSTEMIC SCLEROSIS USING HIGH-THROUGHPUT SEQUENCING

An analysis of abnormalities in the B cell receptor repertoire in patients with systemic sclerosis using high-throughput sequencing

Systemic sclerosis is a chronic multisystem autoimmune disease that is associated with polyclonal B cell hyperreactivity.The CDR3 of BCRs is the major site of antigen recognition.Therefore, we analyzed the BCR repertoire of patients with SSc.The BCR repertoires in 12 subjects including eight SSc patients and four healthy controls were characterized

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MarshCover: A Web-based Tool for Estimating Vegetation Coverage in Marsh Images Using Convolutional Neural Networks

Marsh ecosystems are some of our most important, serving many crucial ecological functions.They are also rapidly changing, and it is vital for scientists to track these changes.This includes monitoring Name Engraving Service the health of marshes via estimating ground coverage by various grass species, a task that requires human labor to look at ma

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Checklist for the preparation and review of pain clinical trial publications: a pain-specific supplement to CONSORT

Abstract.Introduction:.Randomized clinical trials (RCTs) are considered the gold standard when assessing the efficacy of interventions because randomization of treatment assignment minimizes bias in treatment effect estimates.However, if RCTs are not performed with methodological rigor, many opportunities for bias in treatment effect estimates rema

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Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors

Aza-peptide aldehydes and ketones are a new class of reversible protease inhibitors that are specific for the proteasome and clan CD cysteine proteases.We designed and synthesised aza-Leu derivatives that Charcoal Supplements were specific for the chymotrypsin-like active site of the proteasome, aza-Asp derivatives that were effective inhibitors of

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EXPLORATORY ANALYSIS OF RECIDIVISM OF UNREGULATED CIRCULAR MIGRATION AMONG ZIMBABWEAN IRREGULAR FEMALE LABOUR MIGRANT DEPORTEES

Employing an exploratory analysis using a sample of 20 female Zimbabwean deportees from South Africa, the paper looks into the main factors which stimulate repeat of unregulated circular migration.Besides this, the study aimed at providing deep insights into the lived experiences of the deportees who have a preference for repeat migration in its un

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